Anna Linusson Jonsson

Proceedings of the National Academy of Sciences of the United States of America, Proceedings of the National Academy of Sciences (PNAS) 2023, Vol. 120, (22)

Stael, Simon; Sabljić, Igor; Audenaert, Dominique; et al.

Structure-activity relationships reveal beneficial selectivity profiles of inhibitors targeting acetylcholinesterase of disease-transmitting mosquitoes

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2023, Vol. 66, (9) : 6333-6353

Vidal-Albalat, Andreu; Kindahl, Tomas; Rajeshwari, Rajeshwari; et al.

Broad-Spectrum Antidote Discovery by Untangling the Reactivation Mechanism of Nerve-Agent-Inhibited Acetylcholinesterase

Chemistry - A European Journal, John Wiley & Sons 2022, Vol. 28, (40)

Lindgren, Cecilia; Forsgren, Nina; Hoster, Norman; et al.

Probing Fluorinated Motifs onto Dual AChE-MAO B Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Early-ADME Studies

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2022, Vol. 65, (5) : 3962-3977

Rullo, Mariagrazia; Cipolloni, Marco; Catto, Marco; et al.

In Situ Assembly of Choline Acetyltransferase Ligands by a Hydrothiolation Reaction Reveals Key Determinants for Inhibitor Design

Angewandte Chemie International Edition, Wiley-VCH Verlagsgesellschaft 2021, Vol. 60, (2) : 813-819

Wiktelius, Daniel; Allgardsson, Anders; Bergström, Tomas; et al.

Physical Mechanisms Governing Substituent Effects on Arene-Arene Interactions in a Protein Milieu

Journal of Physical Chemistry B, American Chemical Society (ACS) 2020, Vol. 124, (30) : 6529-6539

Andersson, C. David; Mishra, Brijesh Kumar; Forsgren, Nina; et al.

Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases

Molecular Cell, Elsevier 2020, Vol. 77, (5) : 927-929

Minina, Elena A.; Staal, Jens; Alvarez, Vanina E.; et al.

Nucleation of an Activating Conformational Change by a Cation−Π Interaction

Biochemistry, American Chemical Society (ACS) 2019, Vol. 58, (32) : 3408-3412

Rogne, Per; Andersson, David; Grundström, Christin; et al.

Influence of Enantiomeric Inhibitors on the Dynamics of Acetylcholinesterase Measured by Elastic Incoherent Neutron Scattering

Journal of Physical Chemistry B, American Chemical Society (ACS) 2018, Vol. 122, (36) : 8516-8525

Andersson, C. David; Martinez, Nicolas; Zeller, Dominik; et al.

Noncovalent Inhibitors of Mosquito Acetylcholinesterase 1 with Resistance-Breaking Potency

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2018, Vol. 61, (23) : 10545-10557

Knutsson, Sofie; Engdahl, Cecilia; Kumari, Rashmi; et al.

Identification of potential aryl hydrocarbon receptor ligands by virtual screening of industrial chemicals

Environmental Science and Pollution Research, Springer 2018, Vol. 25, (3) : 2436-2449

Larsson, Malin; Fraccalvieri, Domenico; Andersson, C. David; et al.

Dynamics Determine Signaling in a Multicomponent System Associated with Rheumatoid Arthritis

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2018, Vol. 61, (11) : 4774-4790

Lindgren, Cecilia; Tyagi, Mohit; Viljanen, Johan; et al.

Retention-time prediction in comprehensive two-dimensional gas chromatography to aid identification of unknown contaminants

Analytical and Bioanalytical Chemistry, Springer Berlin/Heidelberg 2018, Vol. 410, (30) : 7931-7941

Veenaas, Cathrin; Linusson, Anna; Haglund, Peter

An unusual dimeric inhibitor of acetylcholinesterase: cooperative binding of crystal violet

Molecules, MDPI AG 2017, Vol. 22, (9)

Allgardsson, Anders; Andersson, C. David; Akfur, Christine; et al.

Changes in dynamics of alpha-chymotrypsin due to covalent inhibitors investigated by elastic incoherent neutron scattering

Physical Chemistry, Chemical Physics - PCCP, ROYAL SOC CHEMISTRY 2017, Vol. 19, (37) : 25369-25379

Andersson, David C.; Martinez, N.; Zeller, D.; et al.

N-Aryl-N'-ethyleneaminothioureas effectively inhibit acetylcholinesterase 1 from disease-transmitting mosquitoes

European Journal of Medicinal Chemistry, Vol. 134 : 415-427

Knutsson, Sofie; Kindahl, Tomas; Engdahl, Cecilia; et al.

Structure of a prereaction complex between the nerve agent sarin, its biological target acetylcholinesterase, and the antidote HI-6

Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, (20) : 5514-5519

Allgardsson, Anders; Berg, Lotta; Akfur, Christine; et al.

The Nature of Activated Non-classical Hydrogen Bonds: A Case Study on Acetylcholinesterase-Ligand Complexes

Chemistry - A European Journal, Wiley-VCH Verlagsgesellschaft 2016, Vol. 22, (8) : 2672-2681

Berg, Lotta; Mishra, Brijesh Kumar; Andersson, C. David; et al.

Discovery of selective inhibitors targeting acetylcholinesterase 1 from disease-transmitting mosquitoes

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2016, Vol. 59, (20) : 9409-9421

Engdahl, Cecilia; Knutsson, Sofie; Ekström, Fredrik; et al.

Benefits of statistical molecular design, covariance analysis, and reference models in QSAR: a case study on acetylcholinesterase

Journal of Computer-Aided Molecular Design, Vol. 29, (3) : 199-215

Andersson, C. David; Hillgren, J. Mikael; Lindgren, Cecilia; et al.

Towards small molecule inhibitors of mono-ADP-ribosyltransferases

European Journal of Medicinal Chemistry, Vol. 95 : 546-551

Ekblad, Torun; Lindgren, Anders E. G.; Andersson, C. David; et al.

Acetylcholinesterases from the Disease Vectors Aedes aegypti and Anopheles gambiae: Functional Characterization and Comparisons with Vertebrate Orthologues

PLOS ONE, Vol. 10, (10)

Engdahl, Cecilia; Knutsson, Sofie; Fredriksson, Sten-Åke; et al.

Structural Basis for Lack of ADP-ribosyltransferase Activity in Poly(ADP-ribose) Polymerase-13/Zinc Finger Antiviral Protein

Journal of Biological Chemistry, Vol. 290, (12) : 7336-7344

Karlberg, Tobias; Klepsch, Mirjam; Thorsell, Ann-Gerd; et al.

Hydroxyethylene isosteres introduced in type II collagen fragments substantially alter the structure and dynamics of class II MHC A(q)/glycopeptide complexes

Organic and biomolecular chemistry, Vol. 13, (22) : 6203-6216

Lindgren, Cecilia; Andersson, Ida E.; Berg, Lotta; et al.

Statistical molecular design: a tool to follow up hits from small-molecule screening.

Methods in Molecular Biology, Springer 2014, Vol. 1056 : 169-188

Lindgren, Anders E G; Larsson, Andreas; Linusson, Anna; et al.

Divergent Structure-Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2013, Vol. 56, (19) : 7615-7624

Andersson, C. David; Forsgren, Nina; Akfur, Christine; et al.

Catalytic-site conformational equilibrium in nerve-agent adducts of acetylcholinesterase: Possible implications for the HI-6 antidote substrate specificity

Biochemical Pharmacology, Elsevier 2013, Vol. 85, (9) : 1389-1397

Artursson, Elisabet; Andersson, Per Ola; Akfur, Christine; et al.

On the use of electronic descriptors for QSAR modelling of PCDDs, PCDFs and dioxin-like PCBs^£:

SAR and QSAR in environmental research (Print), Taylor & Francis Group 2013, Vol. 24, (6) : 461-479

Larsson, Malin; Kumar Mishra, Brijesh; Tysklind, Mats; et al.

Chemical Probes to Study ADP-Ribosylation: Synthesis and Biochemical Evaluation of Inhibitors of the Human ADP-Ribosyltransferase ARTD3/PARP3

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2013, Vol. 56, (23) : 9556-9568

Lindgren, Anders E. G.; Karlberg, Tobias; Ekblad, Torun; et al.

PARP Inhibitor with Selectivity Toward ADP-Ribosyltransferase ARTD3/PARP3

ACS Chemical Biology, Vol. 8, (8) : 1698-1703

Lindgren, Anders E. G.; Karlberg, Tobias; Thorsell, Ann-Gerd; et al.

Determinants for simultaneous binding of copper and platinum to human chaperone Atox1: hitchhiking not hijacking

PLOS ONE, Public Library Science 2013, Vol. 8, (7)

Palm-Espling, Maria; Andersson, David C.; Björn, Erik; et al.

Discovery of Ligands for ADP-Ribosyltransferases via Docking-Based Virtual Screening

Journal of Medicinal Chemistry, Vol. 55, (17) : 7706-7718

Andersson, C David; Karlberg, Tobias; Ekblad, Torun; et al.

Angewandte Chemie International Edition, Vol. 51, (51) : 12716-12720

Berg, Lotta; Niemiec, Moritz S.; Qian, Weixing; et al.

Mapping pilicide anti-virulence effect in Escherichia coli, a comprehensive structure-activity study

Bioorganic & Medicinal Chemistry, Elsevier 2012, Vol. 20, (9) : 3128-3142

Chorell, Erik; Pinkner, Jerome S; Bengtsson, Christoffer; et al.

Design of glycopeptides used to investigate class II MHC binding and T-Cell responses associated with autoimmune arthritis

PLOS ONE, Public Library of Science 2011, Vol. 6, (3) : e17881-

Andersson, Ida E; Andersson, C David; Batsalova, Tsvetelina; et al.

(E)-Alkene and Ethylene Isosteres Substantially Alter the Hydrogen-Bonding Network in Class II MHC A^q/Glycopeptide Complexes and Affect T-Cell Recognition

Journal of the American Chemical Society, American Chemical Society 2011, Vol. 133, (36) : 14368-14378

Andersson, Ida E.; Batsalova, Tsvetelina; Haag, Sabrina; et al.

Targeting Acetylcholinesterase: Identification of Chemical Leads by High Throughput Screening, Structure Determination and Molecular Modeling

PLOS ONE, San Francisco: Public Library of Science 2011, Vol. 6, (11)

Berg, Lotta; Andersson, C. David; Artursson, Elisabet; et al.

Postprocessing of docked protein-ligand complexes using implicit solvation models

Journal of chemical information and modeling, Vol. 51, (2) : 267-282

Lindström, Anton; Edvinsson, Lotta; Johansson, Andreas; et al.

Multivariate assessment of virtual screening experiments

Journal of Chemometrics, John Wiley & Sons, Ltd 2010, Vol. 24, (11-12) : 757-767

Andersson, C David; Chen, Brian Y; Linusson, Anna

Mapping of ligand-binding cavities in proteins

Proteins: Structure, Function, and Bioinformatics, John Wiley & Sons, Inc 2010, Vol. 78, (6) : 1408-1422

Andersson, David C.; Chen, Brian Y; Linusson Jonsson, Anna

Oxazole-modified glycopeptides that target arthritis-associated class II MHC A^q and DR4 proteins

Organic and biomolecular chemistry, RSC Publishing 2010, Vol. 8, (13) : 2931-2940

Andersson, Ida E.; Batsalova, Tsvetelina; Dzhambazov, Balik; et al.

Statistical molecular design of a focused salicylidene acylhydrazide library and multivariate QSAR of inhibition of type III secretion in the Gram-negative bacterium Yersinia

Bioorganic & Medicinal Chemistry, Vol. 18, (7) : 2686-2703

Dahlgren, Markus K; Zetterström, Caroline E; Gylfe, Åsa; et al.

Statistical molecular design of balanced compound libraries for QSAR modeling

Current Medicinal Chemistry, Vol. 17, (19) : 2001-2016

Linusson, Anna; Elofsson, Mikael; Andersson, Ida E; et al.

Quantitative protein descriptors for secondary structure characterization and protein classification

Chemometrics and Intelligent Laboratory Systems, Vol. 95, (1) : 74-85

Lindström, Anton; Pettersson, Fredrik; Linusson, Anna

Transthyretin-related and transthyretin-like proteins

Recent advances in Transthyretin evolution, structure and biological functions, Springer Berlin/Heidelberg 2009 : 109-122

Sauer-Eriksson, Elisabeth; Linusson, Anna; Lundberg, Erik

A multivariate chemical map of industrial chemicals: Assessment of various protocols for identification of chemicals of potential concern

Chemosphere, Elsevier 2009, Vol. 76, (7) : 878-884

Stenberg, Mia; Linusson, Anna; Tysklind, Mats; et al.

Visa publikationer i DiVA

Forskargrupper

Forskningsledare

Anna Linusson Lab

Forskningsprojekt

1 december 2018 till 30 november 2023

Nya läkemedel mot nervgas- och insecticidförgiftningar

Publicerad: 08 nov, 2022

Mer än 180 miljoner till ny forskning vid Umeå universitet

Publicerad: 13 mar, 2020

Samverkanspris till läkemedelskemist

Publicerad: 08 apr, 2019

Såddpengar sår frön till nya doktorander i Företagsforskarskolan

Publicerad: 14 jan, 2019

Företagsforskarskolan firar tio år och fortsätter sikta uppåt

Publicerad: 03 maj, 2016

Nya läkemedel mot nervgaser i sikte

Publicerad: 04 nov, 2014

45 miljoner kronor till forskning inom naturvetenskap och teknik

Publicerad: 30 jun, 2014

Med upptäckande som drivkraft

Publicerad: 19 dec, 2013

Ny föreståndare för Företagsforskarskolan