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Rolf Adolfsson
Research qualifications:
Docent
0000-0001-9785-8473
Contact
E-mail
rolf.adolfsson@umu.se
Phone
+46 90 786 69 63
Works as
Affiliation
Professor
at
Department of Clinical Sciences
Section: Psychiatry
Location
23, vån 5, NUS, Psykiatriska kliniken
Umeå universitet, Psykiatri, 901 85 Umeå
Publications
Publications
2025
Fine-mapping genomic loci refines bipolar disorder risk genes
Nature Neuroscience
, Springer Nature 2025, Vol. 28 : 1393-1403
Koromina, Maria; Ravi, Ashvin; Panagiotaropoulou, Georgia; et al.
2025
New genomics discoveries across the bipolar disorder spectrum implicate neurobiological and developmental pathways
Biological Psychiatry
O'Connell, Kevin S.; Adolfsson, Rolf; Andlauer, Till F.M.; et al.
2025
Genomics yields biological and phenotypic insights into bipolar disorder
Nature
, Springer Nature 2025, Vol. 639, (8056) : 968-975
O’Connell, Kevin S.; Adolfsson, Rolf; Andreassen, Ole A.
2025
Associations between air pollution and relative leukocyte telomere length among northern Swedish adults based on findings from the Betula study
Scientific Reports
, Vol. 15, (1)
Raza, Wasif; Pudas, Sara; Kanninen, Katja M.; et al.
2024
The influence of personality traits on engagement in lifelong learning
International Journal of Lifelong Education
, Routledge 2024, Vol. 43, (2-3) : 259-276
Eriksson Sörman, Daniel; Åström, Elisabeth; Ahlström, Mikael; et al.
2024
Revised temperament and character inventory factors predict neuropsychiatric symptoms and aging-related cognitive decline across 25 years
Frontiers in Aging Neuroscience
, Frontiers Media S.A. 2024, Vol. 16
Ronat, Lucas; Rönnlund, Michael; Adolfsson, Rolf; et al.
2023
Pm
2.5
and dementia in a low exposure setting: the influence of odor identification ability and
APOE
Journal of Alzheimer's Disease
, IOS Press 2023, Vol. 92, (2) : 679-689
Andersson, John; Sundström, Anna; Nordin, Maria; et al.
2023
GWAS meta-analysis of suicide attempt: identification of 12 genome-wide significant loci and implication of genetic risks for specific health factors
American Journal of Psychiatry
, American Psychiatric Association Publishing 2023, Vol. 180, (10) : 723-738
Docherty, Anna R.; Mullins, Niamh; Ashley-Koch, Allison E.; et al.
2023
Dissecting the genetic heterogeneity of gastric cancer
EBioMedicine
, Elsevier 2023, Vol. 92
Hess, Timo; Maj, Carlo; Gehlen, Jan; et al.
2023
Memory profiles predict dementia over 23–28 years in normal but not successful aging
International psychogeriatrics
, Cambridge University Press 2023, Vol. 35, (7) : 351-359
Josefsson, Maria; Sundström, Anna; Pudas, Sara; et al.
2023
Sixteen-year longitudinal evaluation of blood-based DNA methylation biomarkers for early prediction of Alzheimer’s disease
Journal of Alzheimer's Disease
, IOS Press 2023, Vol. 94, (4) : 1443-1464
Schäfer Hackenhaar, Fernanda; Josefsson, Maria; Nordin Adolfsson, Annelie; et al.
2022
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Biological Psychiatry
, Elsevier 2022, Vol. 91, (1) : 102-117
Blokland, Gabriëlla A. M.; Grove, Jakob; Chen, Chia-Yen; et al.
2022
Bipolar disorder and bone mineral density z-scores in relation to clinical characteristics and lithium medication
Journal of Clinical Medicine
, MDPI 2022, Vol. 11, (23)
Lassas, Anders; Norrbäck, Karl-Fredrik; Adolfsson, Rolf; et al.
2022
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Biological Psychiatry
, Elsevier 2022, Vol. 91, (3) : 313-327
Mullins, Niamh; Kang, JooEun; Campos, Adrian I.; et al.
2022
The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia
Nature Communications
, Nature Publishing Group 2022, Vol. 13, (1)
Nehme, Ralda; Pietiläinen, Olli; Artomov, Mykyta; et al.
2022
Exome sequencing in bipolar disorder identifies
AKAP11
as a risk gene shared with schizophrenia
Nature Genetics
, Nature Publishing Group 2022, Vol. 54, (5) : 541-547
Palmer, Duncan S.; Howrigan, Daniel P.; Chapman, Sinéad B.; et al.
2022
Association of APOE ɛ4 and Plasma p-tau181 with Preclinical Alzheimer's Disease and Longitudinal Change in Hippocampus Function
Journal of Alzheimer's Disease
, IOS Press 2022, Vol. 85, (3) : 1309-1320
Salami, Alireza; Adolfsson, Rolf; Andersson, Micael; et al.
2022
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Nature
, Springer Nature 2022, Vol. 604, (7906) : 502-508
Trubetskoy, Vassily; Pardiñas, Antonio F.; Qi, Ting; et al.
2021
Antiviral treatment associated with reduced risk of clinical Alzheimer's disease: A nested case-control study
Alzheimer’s & Dementia: Translational Research & Clinical Interventions
, John Wiley & Sons 2021, Vol. 7, (1)
Hemmingsson, Eva-Stina; Hjelmare, Ellen; Weidung, Bodil; et al.
2021
Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder
Molecular Psychiatry
, Springer Nature 2021, Vol. 26 : 5239-5250
Jia, Xiaoming; Goes, Fernando S.; Locke, Adam E.; et al.
2021
Characterisation of age and polarity at onset in bipolar disorder
British Journal of Psychiatry
, Cambridge University Press 2021, Vol. 219, (6) : 659-669
Kalman, Janos L.; Olde Loohuis, Loes M.; Vreeker, Annabel; et al.
2021
Sex-specific effects of polygenic risk for schizophrenia on lifespan cognitive functioning in healthy individuals
Translational Psychiatry
, Springer Nature 2021, Vol. 11, (1)
Koch, Elise; Nyberg, Lars; Lundquist, Anders; et al.
2021
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Nature Genetics
, Nature Publishing Group 2021, Vol. 53, (6) : 817-829
Mullins, Niamh; Forstner, Andreas J.; O’Connell, Kevin S.; et al.
2021
Traffic-Related air pollution as a risk factor for dementia: no clear modifying effects of apoe ɛ4 in the betula cohort
Alzheimer's disease and air pollution: the development and progression of a fatal disease from childhood and the opportunities for early prevention
, Amsterdam: IOS Press 2021 : 357-364
Oudin, Anna; Andersson, John; Sundström, Anna; et al.
2021
Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM
2.5
) and Incidence of Alzheimer's Disease and Dementia: Results from the Betula Cohort in Northern Sweden
Journal of Alzheimer's Disease
, IOS Press 2021, Vol. 81, (1) : 83-85
Oudin Åström, Daniel; Adolfsson, Rolf; Segersson, David; et al.
2021
Short leukocyte telomeres, but not telomere attrition rates, predict memory decline in the 20-year longitudinal Betula study
The journals of gerontology. Series A, Biological sciences and medical sciences
, Oxford University Press 2021, Vol. 76, (6) : 955-963
Pudas, Sara; Josefsson, Maria; Nordin Adolfsson, Annelie; et al.
2021
Short leukocyte telomeres predict 25-year Alzheimer's disease incidence in non-
APOE
ε4-carriers
Alzheimer's Research & Therapy
, BioMed Central (BMC) 2021, Vol. 13
Schäfer Hackenhaar, Fernanda; Josefsson, Maria; Nordin Adolfsson, Annelie; et al.
2020
Effects of polygenic risk for Alzheimer's disease on rate of cognitive decline in normal aging
Translational Psychiatry
, Nature Publishing Group 2020, Vol. 10, (1)
Kauppi, Karolina; Rönnlund, Michael; Nordin Adolfsson, Annelie; et al.
2020
Biological and environmental predictors of heterogeneity in neurocognitive ageing: Evidence from Betula and other longitudinal studies
Ageing Research Reviews
, Elsevier 2020, Vol. 64
Nyberg, Lars; Boraxbekk, Carl-Johan; Eriksson Sörman, Daniel; et al.
2020
Elevated plasma neurofilament light in aging reflects brain white-matter alterations but does not predict cognitive decline or Alzheimer's disease
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring (DADM)
, John Wiley & Sons 2020, Vol. 12, (1)
Nyberg, Lars; Lundquist, Anders; Nordin Adolfsson, Annelie; et al.
2020
Mental demands at work and risk of dementia
Journal of Alzheimer's Disease
, IOS Press 2020, Vol. 74, (3) : 735-740
Sundström, Anna; Eriksson Sörman, Daniel; Hansson, Patrik; et al.
2020
Loneliness increases the risk of all-cause dementia and Alzheimer's disease
The journals of gerontology. Series B, Psychological sciences and social sciences
, Oxford University Press 2020, Vol. 75, (5) : 919-926
Sundström, Anna; Nordin Adolfsson, Annelie; Nordin, Maria; et al.
2019
The genomics of bipolar and schizophrenic disorders in a large pedigree from a northern Swedish isolate
European Neuropsychopharmacology
, Elsevier 2019, Vol. 29 : S902-S903
Crowley, James; Mudgal, Poorva; Nordin Adolfsson, Annelie; et al.
2019
Serum Metabolite Markers of Dementia Through Quantitative NMR Analysis: The Importance of Threonine-Linked Metabolic Pathways
Journal of Alzheimer's Disease
, IOS Press 2019, Vol. 69, (3) : 763-774
Figueira, Joao; Adolfsson, Rolf; Nordin Adolfsson, Annelie; et al.
2019
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Nature Genetics
, Nature Publishing Group 2019, Vol. 51, (4) : 659-+
Huckins, Laura M.; Dobbyn, Amanda; Ruderfer, Douglas M.; et al.
2019
Herpes Simplex Virus,
APOE
ɛ
4, and Cognitive Decline in Old Age: Results from the Betula Cohort Study
Journal of Alzheimer's Disease
, IOS Press 2019, Vol. 67, (1) : 211-220
Lövheim, Hugo; Norman, Tove; Weidung, Bodil; et al.
2019
Quality of life for patients diagnosed with bipolar disorder: lifestyle and treatment
Neurology, psychiatry and brain research
, Elsevier 2019, Vol. 34 : 34-40
Maripuu, Martin; Norrbäck, Karl-Fredrik; Adolfsson, Rolf
2019
GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores
American Journal of Psychiatry
, American Psychiatric Association Publishing 2019, Vol. 176, (8) : 651-660
Mullins, Niamh; Bigdeli, Tim B.; Borglum, Anders D.; et al.
2019
Association of Polygenic Liabilities for Major Depression, Bipolar Disorder, and Schizophrenia With Risk for Depression in the Danish Population
JAMA psychiatry
, Chicago: American Medical Association 2019, Vol. 76, (5) : 516-525
Musliner, Katherine L.; Mortensen, Preben B.; McGrath, John J.; et al.
2019
Traffic-Related Air Pollution as a Risk Factor for Dementia: No Clear Modifying Effects of
APOE
ɛ
4 in the Betula Cohort
Journal of Alzheimer's Disease
, IOS Press 2019, Vol. 71, (3) : 733-740
Oudin, Anna; Andersson, John; Sundström, Anna; et al.
2019
Genome-wide association study identifies 30 loci associated with bipolar disorder
Nature Genetics
, Vol. 51, (5) : 793-803
Stahl, Eli A.; Breen, Gerome; Forstner, Andreas J; et al.
2019
The genomics of major psychiatric disorders in a large pedigree from Northern Sweden
Translational Psychiatry
, Nature Publishing Group 2019, Vol. 9
Szatkiewicz, Jin; Crowley, James J.; Nordin Adolfsson, Annelie; et al.
2019
Genetic variants as modifiers of the association of body mass index with bipolar disorder
European Neuropsychopharmacology
, Elsevier 2019, Vol. 29 : S838-S839
Winham, Stacey; Cuellar-Barboza, Alfredo; Batzler, Anthony; et al.
2019
Depressive symptoms and time perspective in older adults: associations beyond personality and negative life events
Aging & Mental Health
, Routledge 2019, Vol. 23, (12) : 1674-1683
Åström, Elisabeth; Rönnlund, Michael; Adolfsson, Rolf; et al.
2018
Road traffic noise, air pollution, and risk of dementia: results from the Betula project
Environmental Research
, Elsevier 2018, Vol. 166 : 334-339
Andersson, John; Oudin, Anna; Sundström, Anna; et al.
2018
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder
Communications Biology
, Nature Publishing Group 2018, Vol. 1
de Jong, Simone; Abdalla Diniz, Mateus Jose; Saloma, Andiara; et al.
2018
Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission
Cell Reports
, Cell Press 2018, Vol. 23, (8) : 2509-2523
Nehme, Ralda; Zuccaro, Emanuela; Ghosh, Sulagna Dia; et al.
2018
Association between air pollution from residential wood burning and dementia incidence in a longitudinal study in Northern Sweden
PLOS ONE
, Public Library of Science 2018, Vol. 13, (6)
Oudin, Anna; Segersson, David; Adolfsson, Rolf; et al.
2018
Perceived stress in adults aged 65 to 90: Relations to facets of time perspective and COMT Val
158
Met polymorphism
Frontiers in Psychology
, Frontiers Media S.A. 2018, Vol. 9
Rönnlund, Michael; Åström, Elisabeth; Adolfsson, Rolf; et al.
2018
Genome-wide interactions with body mass index and bipolar disorder risk: a study from the psychiatric genomics consortium bipolar disorder working group
Bipolar Disorders
, John Wiley & Sons 2018, Vol. 20 : 110-111
Winham, S.; Cuellar Barboza, A.; Batzler, A.; et al.
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