Miles Trupp

Identification of biomarkers and novel drug targets for neurodegenerative diseases using genomics, metabolomics and proteomics in CSF and blood biobank samples.

Research qualifications: Docent

Contact

miles.trupp@umu.se

Works as

Group leader at Department of Clinical Sciences Section: Neurosciences

Norrlands universitetssjukhus, Umeå universitet, Klinisk vetenskap Umeå universitet, Klinisk vetenskap, 901 85 Umeå

Homozygosity for R47H in TREM2 and the Risk of Alzheimer's Disease

New England Journal of Medicine, Massachusetts Medical Society 2024, Vol. 390, (23) : 2217-2219

Stefansson, Hreinn; Walters, G Bragi; Sveinbjornsson, Gardar; et al.

Prediction and early biomarkers of cognitive decline in Parkinson disease and atypical parkinsonism: a population-based study

Brain Communications, Oxford University Press 2022, Vol. 4, (2)

Bäckström, David C; Granåsen, Gabriel; Jakobson Mo, Susanna; et al.

Label-free detection and quantification of ultrafine particulate matter in lung and heart of mouse and evaluation of tissue injury

Particle and Fibre Toxicology, BioMed Central (BMC) 2022, Vol. 19, (1)

Hameed, Saira; Pan, Kun; Su, Wenhua; et al.

Alterations in Self-Aggregating Neuropeptides in Cerebrospinal Fluid of Patients with Parkinsonian Disorders

Journal of Parkinson's Disease, IOS Press 2022, Vol. 12, (4) : 1169-1189

Zhu, Shaochun; Bäckström, David C; Forsgren, Lars; et al.

The Cerebrospinal Fluid Profile of Cholesterol Metabolites in Parkinson’s Disease and Their Association With Disease State and Clinical Features

Frontiers in Aging Neuroscience, Frontiers Media S.A. 2021, Vol. 13

Griffiths, William J.; Abdel-Khalik, Jonas; Moore, Sarah F.; et al.

Deep mining of oxysterols and cholestenoic acids in human plasma and cerebrospinal fluid: Quantification using isotope dilution mass spectrometry

Analytica Chimica Acta, Elsevier 2021, Vol. 1154

Yutuc, Eylan; Dickson, Alison L.; Pacciarini, Manuela; et al.

Polyunsaturated Fatty Acids and Their Metabolites in Hyperemesis Gravidarum

Nutrients, MDPI 2020, Vol. 12, (11)

Lindberg, Richard; Lindqvist, Maria; Trupp, Miles; et al.

General and abdominal adiposity and the risk of Parkinson's disease: A prospective cohort study

Parkinsonism & Related Disorders, ELSEVIER SCI LTD 2019, Vol. 62 : 98-104

Riso, Lukas; Kaaks, Rudolf; Kuehn, Tilman; et al.

Targeted Multiple Reaction Monitoring Analysis of CSF Identifies UCHL1 and GPNMB as Candidate Biomarkers for ALS

Journal of Molecular Neuroscience, Springer 2019, Vol. 69, (4) : 643-657

Zhu, Shaochun; Wuolikainen, Anna; Wu, Junfang; et al.

NMR analysis of the CSF and plasma metabolome of rigorously matched amyotrophic lateral sclerosis, Parkinson's disease and control subjects

Metabolomics, Vol. 12, (6)

Wu, Junfang; Wuolikainen, Anna; Trupp, Miles; et al.

Multi-platform mass spectrometry analysis of the CSF and plasma metabolomes of rigorously matched amyotrophic lateral sclerosis, Parkinson's disease and control subjects

Molecular Biosystems, Vol. 12, (4) : 1287-1298

Wuolikainen, Anna; Jonsson, Pär; Ahnlund, Maria; et al.

Cerebrospinal Fluid Patterns and the Risk of Future Dementia in Early, Incident Parkinson Disease

JAMA Neurology, American Medical Association 2015, Vol. 72, (10) : 1175-1182

Bäckström, David C; Eriksson Domellöf, Magdalena; Linder, Jan; et al.

Metabolite and peptide levels in plasma and CSF differentiating healthy controls from patients with newly diagnosed Parkinson's disease

Journal of Parkinson's Disease, Taylor & Francis 2014, Vol. 4, (3) : 549-560

Trupp, Miles; Jonsson, Pär; Öhrfelt, Annika; et al.

View publications in DiVA

Research groups

Hyperemesis Gravidarum Research in Umeå