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Staff photo Karolis Vaitkevicius

Karolis Vaitkevicius

I am a staff scientist working in research groups of Jörgen Johansson and Jan Larsson.

My main areas of interest are RNA or RNA-protein biology, and associated interactions and regulation.

Contact

E-mail
karolis.vaitkevicius@umu.se
Phone
+46 90 785 67 39

Works as

Affiliation
Staff scientist at Department of Molecular Biology Section: Research group Jörgen Johansson
Location
6K och 6L, Sjukhusområdet Umeå universitet, 901 87 Umeå
A highly substituted ring-fused 2-pyridone compound targeting PrfA and the efflux regulator BrtA in listeria monocytogenes
mBio, American Society for Microbiology 2023, Vol. 14, (3)
Tükenmez, Hasan; Singh, Pardeep; Sarkar, Souvik; et al.
Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes
Nucleic Acids Research, Oxford University Press 2022, Vol. 50, (19) : 11285-11300
Koller, Timm O.; Turnbull, Kathryn Jane; Vaitkevicius, Karolis; et al.
Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens
Nature Communications, Springer Nature 2021, Vol. 12, (1)
Crowe-McAuliffe, Caillan; Murina, Victoriia; Turnbull, Kathryn Jane; et al.
An mRNA-mRNA Interaction Couples Expression of a Virulence Factor and Its Chaperone in Listeria monocytogenes
Cell Reports, cell press 2020, Vol. 30, (12) : 4027-+
Ignatov, Dmitriy; Vaitkevicius, Karolis; Durand, Sylvain; et al.
Generation of Sequencing Libraries for Structural Analysis of Bacterial 5′ UTRs
STAR Protocols, Vol. 1, (2)
Ignatov, Dmitriy; Vaitkevicius, Karolis; Johansson, Jörgen
Attenuating Listeria monocytogenes virulence by targeting the regulatory protein PrfA
Cell chemical biology, Vol. 23, (3) : 404-414
Good, James A. D.; Andersson, Christopher; Hansen, Sabine; et al.
RNA helicase important for Listeria monocytogenes hemolytic activity and virulence factor expression
Infection and Immunity, American Society for Microbiology 2016, Vol. 84, (1) : 67-76
Netterling, Sakura; Bäreclev, Caroline; Vaitkevicius, Karolis; et al.
DExD-box RNA-helicases in Listeria monocytogenes are important for growth, ribosomal maturation, rRNA processing and virulence factor expression
RNA Biology, Vol. 11, (11) : 1458-1467
Bäreclev, Caroline; Vaitkevicius, Karolis; Netterling, Sakura; et al.
An unstructured 5'-coding region of the prfA mRNA is required for efficient translation
Nucleic Acids Research, Oxford, England: Oxford University Press 2012, Vol. 40, (4) : 1818-1827
Loh, Edmund; Memarpour, Faranak; Vaitkevicius, Karolis; et al.
A listeria monocytogenes RNA-helicase essential for growth and ribosomal maturation at low temperatures, uses its C-terminus for appropriate interaction with the ribosome
Journal of Bacteriology, Vol. 194, (16) : 4377-4385
Netterling, Sakura; Vaitkevicius, Karolis; Nord, Stefan; et al.
Outer membrane vesicle-mediated release of cytolethal distending toxin (CDT) from Campylobacter jejuni
BMC Microbiology, Vol. 16, (9) : 220-
Lindmark, Barbro; Rompikuntal, Pramod Kumar; Vaitkevicius, Karolis; et al.
A trans-acting riboswitch controls expression of the virulence regulator PrfA in Listeria monocytogenes
Cell, Vol. 139, (4) : 770-779
Loh, Edmund; Dussurget, Olivier; Gripenland, Jonas; et al.
Vibrio cholerae cytolysin causes an inflammatory response in human intestinal epithelial cells that is modulated by the PrtV protease
PLOS ONE, San Francisco: Public Library of Science 2009, Vol. 4, (11)
Ou, Gangwei; Rompikuntal, Pramod Kumar; Bitar, Aziz; et al.
Vibrio cholerae cytolysin causes an inflammatory response in human intestinal cells that is modulated by the protease PrtV secreted by the same bacterium
Ou, Gangwei; Vaitkevicius, Karolis; Bitar, Aziz; et al.
The Listeria transcriptional landscape from saprophytism to virulence
Nature, Vol. 459, (7249) : 950-956
Toledo-Arana, Alejandro; Dussurget, Olivier; Nikitas, Georgios; et al.
Role of melanin pigment in expression of Vibrio cholerae virulence factors
Infection and Immunity, American Society for Microbiology 2009, Vol. 77, (3) : 935-942
Valeru, Soni Priya; Rompikuntal, Pramod Kumar; Ishikawa, Takahiko; et al.
The metalloprotease PrtV from Vibrio cholerae
The FEBS Journal, Vol. 275, (12) : 3167-3177
Vaitkevicius, Karolis; Rompikuntal, Pramod Kumar; Lindmark, Barbro; et al.
Effects of Vibrio cholerae protease and pigment production on environmental survival and host interaction
Umeå University medical dissertations, 1144
Vaitkevicius, Karolis
A Vibrio cholerae protease needed for killing of Caenorhabditis elegans has a role in protection from natural predator grazing
Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, (24) : 9280-9285
Vaitkevicius, Karolis; Lindmark, Barbro; Ou, Gangwei; et al.
Rli38, a novel stress induced small RNA required for Listeria monocytogenes virulence
Gripenland, Jonas; Dussurget, Olivier; Sesto, Nina; et al.
The PrtV protease in Vibrio cholerae influenses expression of the VCC/HlyA cytolytic activity
Vaitkevicius, Karolis; Lindmark, Barbro; Rompikuntal, Pramod Kumar; et al.
View publications in DiVA

Research groups

Group member
Jan Larsson Lab
Jörgen Johansson Lab

Research projects

1 January 2021 until 31 December 2024
Chromosomal Gene Regulatory Systems and Chromosome-Specific Adaptations