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Staff photo Jose Antonio Flores Gonzalez

Jose Antonio Flores Gonzalez

PhD student in Iker Valle Aramburu’s group, working on the discovery and functional characterization of microproteins involved in innate immune signalling.

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Affiliation
Doctoral student at Department of Molecular Biology Section: Group Iker Aramburu
Location
6K och 6L, Sjukhusområdet Umeå universitet, 901 87 Umeå

My academic background is in biotechnology and Computational Biology. I completed my MSc in Computational Biology at the Polytechnic University of Madrid (UPM), where I graduated top of my class and developed a strong interest in protein structure, design, and large-scale data analysis. During my Master’s thesis, I explored computational protein engineering using deep learning and structural modelling, which strengthened my motivation to combine in silico approaches with experimental biology.

In September 2025, I joined the Iker Aramburu Lab as a PhD student. The group focuses on the discovery and characterization of microproteins, small and often overlooked translation products that are emerging as important regulators across diverse cellular processes.

My PhD project aims to identify and functionally study novel microproteins involved in innate immune signaling, particularly within nucleic-acid sensing pathways. To achieve this, I combine computational and experimental validation approaches, integrating sequence-based discovery, structural insights, and functional assays.

Through this multidisciplinary approach, my goal is to uncover previously uncharacterized microproteins and shed light on their roles in shaping immune responses.

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