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Staff photo Jan Axelsson

Jan Axelsson

I am working with projects as the PET (Positron Emission Tomography) expert. 

Contact

E-mail
jan.axelsson@umu.se
Phone
+46 90 785 84 35

Works as

Affiliation
Other position at Department of Diagnostics and Intervention Section: Biomedical engineering and Radiation Physics
Location
10 C, Norrlands universitetssjukhus Umeå universitet, 901 85 Umeå

I am working with projects as the PET (Positron Emission Tomography) expert. This involves data acquisition, pharmacokinetic modeling, methodological questions and method development. I have been working with PET physics since 2003. 

Characterizing long- and short-survival glioblastoma patients with FLT-PET/MRI and metabolomics
Neuro-Oncology Advances, Oxford University Press 2025, Vol. 7, (1)
Axelsson, Jan; Björkblom, Benny; Asklund, Thomas; et al.
qDESH: a method to quantify disproportionately enlarged subarachnoid space hydrocephalus
Fluids and Barriers of the CNS, Vol. 22, (1)
Behndig, Sofia; Lalou, Afroditi D.; Axelsson, Jan; et al.
Local staging of de novo prostate cancer using mpMRI, PSMA-PET and PSMA-PET/mpMRI: a comparative study
EJNMMI Research, Springer Nature 2025, Vol. 15, (1)
Grefve, Josefine; Strandberg, Sara; Jonsson, Joakim; et al.
10-year longitudinal dopamine D2-receptor losses are associated with cognitive decline in healthy aging
Cerebral Cortex, Oxford University Press 2025, Vol. 35, (11)
Lundgren, Erik; Lindenberger, Ulman; Lövdén, Martin; et al.
Ultra-hypofractionated radiotherapy with focal boost for high-risk localized prostate cancer (HYPO-RT-PC-boost): in silico evaluation with histological reference
Acta Oncologica, MJS Publishing 2025, Vol. 64 : 1482-1488
Nilsson, Erik; Nilsson, Anneli; Jonsson, Joakim; et al.
Aging-related losses in dopamine D2/3 receptor availability are linked to working-memory decline across five years
Cerebral Cortex, Oxford University Press 2025, Vol. 35, (2)
Papenberg, Goran; Karalija, Nina; Salami, Alireza; et al.
Evaluation of MRI characterisation of histopathologically matched lymph nodes and other mesorectal nodal structures in rectal cancer
European Radiology, Springer Nature 2025, Vol. 35 : 4080-4090
Rutegård, Miriam Kheira; Båtsman, Malin; Blomqvist, Lennart; et al.
Cognitive manifestations and brain integrity in hereditary transthyretin amyloidosis: a systematic review
Journal of Neurology, Springer Nature 2025, Vol. 272, (6)
Senem, Iara; Conde, Rodrigo Melo; Foss, Maria Paula; et al.
Exploring cognitive functions and brain structure in hereditary transthyretin amyloidosis using brain MRI and neuropsychological assessment
Neurological Sciences, Springer Nature 2025, Vol. 46 : 1349-1358
Senem, Iara; Foss, Maria Paula; Lavigne-Moreira, Carolina; et al.
Histopathology-validated gross tumor volume delineations of intraprostatic lesions using PSMA-positron emission tomography/multiparametric magnetic resonance imaging
Physics and Imaging in Radiation Oncology, Elsevier 2024, Vol. 31
Grefve, Josefine; Söderkvist, Karin; Gunnlaugsson, Adalsteinn; et al.
Dopamine release in human associative striatum during reversal learning
Nature Communications, Springer Nature 2024, Vol. 15, (1)
Grill, Filip; Guitart-Masip, Marc; Johansson, Jarkko; et al.
Amphetamine-induced dopamine release in rat: Whole-brain spatiotemporal analysis with [11C]raclopride and positron emission tomography
Journal of Cerebral Blood Flow and Metabolism, Sage Publications 2024, Vol. 44, (3) : 434-445
Johansson, Jarkko; Ericsson, Madelene; Axelsson, Jan; et al.
Longitudinal support for the correlative triad among aging, dopamine D2-like receptor loss, and memory decline
Neurobiology of Aging, Vol. 136 : 125-132
Karalija, Nina; Papenberg, Goran; Johansson, Jarkko; et al.
The influence of hippocampal dopamine D2 receptor losses on episodic-memory decline across 5 years is moderated by BDNF and KIBRA polymorphisms
Cortex, Elsevier 2024, Vol. 176 : 53-61
Papenberg, Goran; Karalija, Nina; Johansson, Jarkko; et al.
Impact of simulated reduced injected dose on the assessment of amyloid PET scans
European Journal of Nuclear Medicine and Molecular Imaging, Vol. 51, (3) : 734-748
Young, Peter; Heeman, Fiona; Axelsson, Jan; et al.
Accuracy of gross tumour volume delineation with [68Ga]-PSMA-PET compared to histopathology for high-risk prostate cancer
Acta Oncologica, MJS Publishing, Medical Journals Sweden 2024, Vol. 63 : 503-510
Zarei, Maryam; Wallstén, Elin; Grefve, Josefine; et al.
Reliability and validity of visual analysis of [18F]FE-PE2I PET/CT in early Parkinsonian disease
Nuclear medicine communications, Wolters Kluwer 2023, Vol. 44, (5) : 397-406
af Bjerkén, Sara; Axelsson, Jan; Larsson, Anne; et al.
Striatal dopamine transporter and receptor availability correlate with relative cerebral blood flow measured with [11C]PE2I, [18F]FE-PE2I and [11C]raclopride PET in healthy individuals
Journal of Cerebral Blood Flow and Metabolism, Sage Publications 2023, Vol. 43, (7) : 1206-1215
Jonasson, My; Frick, Andreas; Fazio, Patrik; et al.
Deep learning-based filling of incomplete sinograms from low-cost, long axial field-of-view PET scanners with inter-detector gaps
The international networking symposiumon artificial intelligence and informatics in nuclear medicine: Program book, University Medical Center Groningen 2023 : 59-59
Leffler, Klara; Tommaso Luppino, Luigi; Kuttner, Samuel; et al.
The grade of individual prostate cancer lesions predicted by magnetic resonance imaging and positron emission tomography
Communications Medicine, Springer Nature 2023, Vol. 3, (1)
Nilsson, Erik; Sandgren, Kristina; Grefve, Josefine; et al.
O304 ameliorates hyperglycemia in mice by dually promoting muscle glucose effectiveness and preserving β-cell function
Communications Biology, Springer Nature 2023, Vol. 6, (1)
Norlin, Stefan; Axelsson, Jan; Ericsson, Madelene; et al.
Visualizing increased uptake of [18F]FDG and [18F]FTHA in kidneys from obese high-fat diet fed C57BL/6J mice using PET/CT ex vivo
PLOS ONE, Public Library of Science (PLoS) 2023, Vol. 18
Nyrén, Rakel; Scherman, Henrik; Axelsson, Jan; et al.
Association of pre-diagnostic physical exercise and peri-diagnostic body composition with mortality in non-metastatic colorectal cancer
International Journal of Colorectal Disease, Springer Nature 2023, Vol. 38, (1)
Renman, David; van Guelpen, Bethany; Anderson, Fredrick; et al.
Histopathology-validated lesion detection rates of clinically significant prostate cancer with mpMRI, [68Ga]PSMA-11-PET and [11C]Acetate-PET
Nuclear medicine communications, Lippincott Williams & Wilkins 2023, Vol. 44, (11) : 997-1004
Sandgren, Kristina; Strandberg, Sara; Jonsson, Joakim; et al.
Widespread fMRI BOLD signal overactivations during cognitive control in older adults are not matched by corresponding increases in fPET glucose metabolism
Journal of Neuroscience, Society for Neuroscience 2023, Vol. 43, (14) : 2527-2536
Stiernman, Lars; Grill, Filip; McNulty, Charlotte; et al.
Verification of multi-structure targeting in chronic microelectrode brain recordings from CT scans
Journal of Neuroscience Methods, Elsevier 2022, Vol. 382
Censoni, Luciano; Halje, Pär; Axelsson, Jan; et al.
The Aged Striatum: Evidence of Molecular and Structural Changes Using a Longitudinal Multimodal Approach in Mice
Frontiers in Aging Neuroscience, Frontiers Media S.A. 2022, Vol. 14
Giacobbo, B.; Özalay, Özgun; Mediavilla, Tomás; et al.
Dopamine and reward-related vigor in younger and older adults
Neurobiology of Aging, Elsevier 2022, Vol. 118 : 34-43
Hird, Emily J.; Beierholm, Ulrik; De Boer, Lieke; et al.
VNTR polymorphism in the SLC6A3 gene does not influence dopamine transporter availability measured by [18F]FE-PE2I PET or [123I]FP-Cit SPECT
Nuclear medicine communications, Wolters Kluwer 2022, Vol. 43, (3) : 247-255
Jakobson Mo, Susanna; Axelsson, Jan; J. Stiernman, Lars; et al.
Validation of dynamic [18F]FE-PE2I PET for estimation of relative regional cerebral blood flow: a comparison with [15O]H2O PET
EJNMMI Research, Springer Science+Business Media B.V. 2022, Vol. 12, (1)
Jakobson Mo, Susanna; Axelsson, Jan; Jonasson, Lars S.; et al.
Does 18F-FDG PET/CT change the surgical management of potentially resectable colorectal liver metastases?
Scandinavian Journal of Surgery, Sage Publications 2022, Vol. 111, (1)
Jonsson, Josefin; Hemmingsson, Oskar; Strengbom, Rebecca; et al.
Longitudinal Dopamine D2 Receptor Changes and Cerebrovascular Health in Aging
Neurology, Vol. 99, (12) : e1278-e1289
Karalija, Nina; Johansson, Jarkko; Papenberg, Goran; et al.
Cerebellar and Cerebral Amyloid Visualized by [18F]flutemetamol PET in Long-Term Hereditary V30M (p.V50M) Transthyretin Amyloidosis Survivors
Frontiers in Neurology, Frontiers Media S.A. 2022, Vol. 13
Unéus, Erica Irene; Wilhelmsson, Christer; Bäckström, David; et al.
N-acetylcysteine decreases dopamine transporter availability in the non-lesioned striatum of the 6-OHDA hemiparkinsonian rat
Neuroscience Letters, Elsevier 2022, Vol. 770
Virel, Ana; Johansson, Jarkko; Axelsson, Jan; et al.
Role of dopamine and gray matter density in aging effects and individual differences of functional connectomes
Brain Structure and Function, Springer 2021, Vol. 226, (3) : 743-758
Garzón, Benjamín; Lövdén, Martin; de Boer, Lieke; et al.
Dissecting Motor and Cognitive Component Processes of a Finger-Tapping Task With Hybrid Dopamine Positron Emission Tomography and Functional Magnetic Resonance Imaging
Frontiers in Human Neuroscience, Frontiers Media S.A. 2021, Vol. 15
Grill, Filip; Johansson, Jarkko; Axelsson, Jan; et al.
Dissociations between glucose metabolism and blood oxygenation in the human default mode network revealed by simultaneous PET-fMRI
Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, (27)
Jonasson Stiernman, Lars; Grill, Filip; Hahn, Andreas; et al.
Sex differences in dopamine integrity and brain structure among healthy older adults: Relationships to episodic memory
Neurobiology of Aging, Elsevier 2021, Vol. 105 : 272-279
Karalija, Nina; Papenberg, Goran; Wåhlin, Anders; et al.
Cerebral blood flow measurements with 15O-water PET using a non-invasive machine-learning-derived arterial input function
Journal of Cerebral Blood Flow and Metabolism, Sage Publications 2021, Vol. 41, (9) : 2229-2241
Kuttner, Samuel; Wickstrøm, Kristoffer Knutsen; Lubberink, Mark; et al.
Cardiac transthyretin amyloidosis 99mTc-DPD SPECTcorrelates with strain echocardiography and biomarkers
European Journal of Nuclear Medicine and Molecular Imaging, Springer 2021, Vol. 48 : 1822-1832
Löfbacka, Viktor; Axelsson, Jan; Pilebro, Björn; et al.
Registration of histopathology to magnetic resonance imaging of prostate cancer
Physics and Imaging in Radiation Oncology, Elsevier 2021, Vol. 18 : 19-25
Sandgren, Kristina; Nilsson, Erik; Keeratijarut Lindberg, Angsana; et al.
Corticostriatal White Matter Integrity and Dopamine D1 Receptor Availability Predict Age Differences in Prefrontal Value Signaling during Reward Learning
Cerebral Cortex, Oxford University Press 2020, Vol. 30, (10) : 5270-5280
de Boer, Lieke; Garzón, Benjamín; Axelsson, Jan; et al.
Microscopic Structure of Frontal White Matter Predict Delay Discounting
Biological Psychiatry, Elsevier 2020, Vol. 87, (9) : S197-S197
Guitart-Masip, Marc; Kurth-Nelson, Zeb; Axelsson, Jan; et al.
Machine learning derived input-function in a dynamic 18F-FDG PET study of mice
Biomedical Engineering & Physics Express, Institute of Physics Publishing (IOPP) 2020, Vol. 6, (1)
Kuttner, Samuel; Wickstrøm, Kristoffer Knutsen; Kalda, Gustav; et al.
Quantification of cardiac amyloid with [18F]Flutemetamol in patients with V30M hereditary transthyretin amyloidosis
Amyloid: Journal of Protein Folding Disorders, Taylor & Francis 2020, Vol. 27, (3) : 191-199
Möckelind, Sofia; Axelsson, Jan; Pilebro, Björn; et al.
Balance between Transmitter Availability and Dopamine D2 Receptors in Prefrontal Cortex Influences Memory Functioning
Cerebral Cortex, Oxford University Press 2020, Vol. 30 : 989-1000
Papenberg, Goran; Karalija, Nina; Salami, Alireza; et al.
Rectal cancer: a methodological approach to matching PET/MRI to histopathology
Cancer Imaging, BioMed Central (BMC) 2020, Vol. 20, (1)
Rutegård, Miriam; Båtsman, Malin; Blomqvist, Lennart; et al.
Body composition measured by computed tomography is associated with colorectal cancer survival, also in early-stage disease
Acta Oncologica, Taylor & Francis 2020, Vol. 59, (7) : 799-808
Shirdel, Mona; Anderson, Fredrick; Myte, Robin; et al.
Improved PET/MRI attenuation correction in the pelvic region using a statistical decomposition method on T2-weighted images
EJNMMI Physics, Springer 2020, Vol. 7, (1)
Wallstén, Elin; Axelsson, Jan; Jonsson, Joakim; et al.
Dorsal striatal dopamine D1 receptor availability predicts an instrumental bias in action learning
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences 2019, Vol. 116, (1) : 261-270
de Boer, Lieke; Axelsson, Jan; Chowdhury, Rumana; et al.
View publications in DiVA

Research groups

Group member
Hanna Nyström lab
Maria Sandström

Research projects

1 May 2023 until 1 May 2032
Prognostic and diagnostic added value of medical imaging in staging and treatment planning of gynecological cancer (PRODIGYN)
1 January 2017
Levermetastaser
1 November 2015 until 1 June 2020
PEARL-PD
1 January 2014
COBRA