Changchun Chen

Research qualifications: Docent

Contact

Works as

Associate professor at Department of Molecular Biology Section: Group Changchun Chen

6K och 6L, Sjukhusområdet Umeå universitet, 901 87 Umeå

Changchun Chen was recruited in Spring 2018 from Cambridge, United Kingdom to Umeå University as a Wallenberg Molecular Medicine Fellow. He is employed as associate professor at UCMM, the Faculty of Medicine.

Shaker/Kv1 potassium channel SHK-1 protects against pathogen infection and oxidative stress in C. elegans

PLOS Genetics, Public Library of Science (PLoS) 2025, Vol. 21, (2)

Pu, Longjun; Wang, Jing; Nilsson, Lars; et al.

Iterative editing of multiple genes using CRISPR/Cas9 in C. elegans

microPublication Biology

Pu, Longjun; Nilsson, Lars; Chen, Changchun; et al.

Dissecting the genetic landscape of GPCR signaling through phenotypic profiling in C. elegans

Nature Communications, Springer Nature 2023, Vol. 14

Pu, Longjun; Wang, Jing; Lu, Qiongxuan; et al.

Hypoxia induces food leaving in C. elegans

microPublication Biology

Pu, Longjun; Zhao, Lina; Lu, Qiongxuan; et al.

ROS and cGMP signaling modulate persistent escape from hypoxia in Caenorhabditis elegans

PLoS biology, PLOS 2022, Vol. 20, (6)

Zhao, Lina; Fenk, Lorenz A.; Nilsson, Lars; et al.

Natural Variation in a Dendritic Scaffold Protein Remodels Experience-Dependent Plasticity by Altering Neuropeptide Expression

Neuron, Elsevier 2020, Vol. 105, (1) : 106-121

Beets, Isabel; Zhang, Gaotian; Fenk, Lorenz A.; et al.

MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity

Nature Communications, Nature Publishing Group 2020, Vol. 11, (1)

Flynn, Sean M; Chen, Changchun; Artan, Murat; et al.

Genetic dissection of neuropeptide cell biology at high and low activity in a defined sensory neuron.

Proceedings of the National Academy of Sciences of the United States of America, Proceedings of the National Academy of Sciences of the United States of America (PNAS) 2018, Vol. 115, (29) : E6890-E6899

Laurent, Patrick; Ch'ng, QueeLim; Jospin, Maëlle; et al.

IL-17 is a neuromodulator of Caenorhabditis elegans sensory responses

Nature, Nature Publishing Group 2017, Vol. 542, (7639) : 43-48

Chen, Changchun; Itakura, Eisuke; Nelson, Geoffrey M.; et al.

Decoding a neural circuit controlling global animal state in C. elegans.

eLIFE, eLife Sciences Publications 2015, Vol. 4

Laurent, Patrick; Soltesz, Zoltan; Nelson, Geoffrey M.; et al.

An ER Complex of ODR-4 and ODR-8/Ufm1 Specific Protease 2 Promotes GPCR Maturation by a Ufm1-Independent Mechanism

PLOS Genetics, Public Library of Science 2014, Vol. 10, (3)

Chen, Changchun; Itakura, Eisuke; Weber, Katherine P; et al.

Familial dysautonomia (FD) patients have reduced levels of the modified wobble nucleoside mcm(5)s(2)U in tRNA

Biochemical and Biophysical Research Communications - BBRC, Vol. 454, (3) : 441-445